to [live] out of a suitcase
/lˈaɪv ˌaʊɾəv ɐ sˈuːtkeɪs/
phrase
to briefly live in one or several places, without ever unpacking one's luggage, often due to not having a permanent place to live or stay in
"Live out of suitcase."
"The traveling salesman was constantly on the road, forced to live out of a suitcase for months at a time."
itchy feet
/ˈɪtʃi fˈiːt/
noun
a strong urge to travel or leave somewhere
"She has itchy feet this summer."
"After two years in the same city he gets itchy feet and decides to move to another country."
the call of the wild
/ðə kˈɔːl ʌvðə wˈaɪld/
phrase
the instinctive desire to return to a more primitive, untamed way of life, often associated with the wilderness or natural world
"He felt the call of the wild and went camping."
"The adventurer could not resist the call of the wild and decided to explore the uncharted jungle alone."
to [hit] the road
/hˈɪt ðə ɹˈoʊd/
phrase
to leave a location, usually to embark on a journey or trip
"We should hit the road before it gets dark."
"We should hit the road early tomorrow morning to avoid the heavy traffic on the highway."
to [test] the waters
/tˈɛst ðə wˈɔːɾɚz/
phrase
to examine the chances of something's success before trying it
"Test the waters first."
"Before launching the new product, the company decided to test the waters with a small focus group."
on the road
/ɔn ðə roʊd/
phrase
in an active state of travel by car, bus, or other form of transportation
"We are on the road."
"The band is on the road for their international tour, performing in a different city each night."